Knee Pain Specialist

Dr. Stem Cell

Regenerative orthopedics located in Encino, Ventura County, Calabasas and Los Angeles, CA

Patients increasingly seek stem cell therapy to repair the tissue damage responsible for ongoing knee pain. Bruce Fishman, MD, MPH, FICS, Melat Haile, FNP, and the team at Dr. Stem Cell have extensive experience with stem cell treatment, delivering optimal results with minimal downtime. If you’re interested in stem cell therapy to relieve your knee pain, call one of the offices in Encino, California, or book a consultation online.

Knee Pain Q & A

What types of knee pain benefit from stem cell therapy?

If you have knee pain, chances are you have other symptoms brought on by the underlying condition causing your pain, such as knee instability, loss of motion, inflammation, tenderness, and difficulty walking.  

The team at Stem Cell Institute of Los Angeles offers cellular therapy to relieve symptoms from many knee conditions, including: 


Osteoarthritis commonly affects large joints that support weight and movement such as your knee. The condition develops as repetitive movement wears down the articular cartilage and allows bones to grate against one another when you move. 

Rheumatoid arthritis is an autoimmune condition that typically begins in small joints like your toes and fingers, but it can spread to your knee. As your immune system attacks the synovial tissues lining the joint, the tissues become inflamed and painful.  

Patellar tendinitis (jumper's knee)

Patellar tendinitis develops when the patellar tendon becomes inflamed. Though this injury often occurs due to activities that involve jumping and landing, it affects anyone who spends time kneeling. 

The band stabilizes your knee during strenuous activities, such as running. Repeatedly flexing and extending your knee causes inflammation and pain. 

Patellofemoral pain syndrome (chondromalacia)

Patellofemoral pain syndrome refers to pain in the front of your knee and around the kneecap, and it’s caused by repetitive stress, muscle imbalances, and injuries. 


How does cellular and acellular therapy alleviate knee pain?

Adult stem cells live throughout your body. When you’re injured, Stem Cells migrate to the damaged area and perform multiple tasks: They regenerate new tissues to repair the injury, regulate inflammation, and release biochemicals such as nanovesicles and cytokines that stimulate healing. 

When you receive cell-based therapy, a concentrated number of cellular elements are injected into the injured tissues in your knee. The injected cells relieve your knee pain as they reduce inflammation and signal your inured tissue to heal. 


Where do the cellular and acellular tissues come from?

We use mesenchymal signaling cells and nanovesicles because they help regenerate tissues such as tendons, ligaments, muscles, and cartilage. Our mesenchymal signaling cells are harvested from the Umbilical Cord (M.S.C.). We obtained them from an FDA Certified Transplant Laboratory. Our staff has personally toured the facility to ensure the highest quality and standards for our patients. 


What should I expect before and during cell-based therapy?

If you have knee pain and you’re interested in cellular therapy, it starts with an initial consultation at Dr. Stem Cell (818)808-2828 to determine if you’re a good candidate for cellular treatment. 

Dr. Fishman performs a complete exam, including X-rays, and may order a updated MRI, CT, or nerve study to evaluate the source of your knee pain. If you’re approved for cellular therapy, - 

Before your cellular treatment you will receive our unique IV infusion treatment containing vitamins, peptides and proteins. This will boost your cellular function and enhance your response to cellular treatment. You will then be sent for Hyperbaric Oxygen Treatment within 24 hours post injection to support your cellular therapy.  

Dr. Fishman then uses fluoroscopic or ultrasound guidance to inject the biologic material precisely at the damaged tissues that are causing your knee pain. 

In some cases, Dr. Fishman may mix the cellular material with platelet-rich plasma (PRP) and alpha-2 macroglobulin (α2M), which supports and accelerates healing. They produce PRP in the office from a sample of your blood. 

Most patients need only one cellular therapy injection for each damaged joint, to alleviate their knee pain.  

You will follow up with Dr. Fishman 4 weeks after your cellular procedure. Depending on your customized protocol for your injury, you may have your first FDA approved muscle building Emsculpt treatment or a Physical Therapy session if appropriate to your condition.  

You need to rest for a few days after your procedure, and you’ll notice that your knee pain improves over the next few months as the cellular biologics rebuild tissues and rehabilitate your injury. You will have regular follow-ups with your doctor at 3, 6 and 12 months to document your improvement.  

If you suffer from chronic knee pain, call Dr. Stem Cell (818)808-2829or email to book an appointment.